fbpx Avissa Skin | Platelet Rich Fibrin (PRF)




Platelet Therapy has become a highly sought-after non-surgical procedure for facial and skin rejuvenation as well as hair restoration.

Platelet-Rich-Fibrin ( PRF ), Platelet-Rich-Plasma ( PRP ) or the all-natural Bio-Filler ( Aka. EZGel or Plasma-Gel ) refer to a series of treatments which uses your own blood’s platelets, proteins, growth-factors, plasma, stem cell, and other regenerative cells to:

Stimulate collagen production
Promote fibroblast formation
Enhance blood flow
Restore volume & hydration
Improve skin texture & quality
Improve under eye dark circles
Benefit acne scars
Accelerate wound healing
Rejuvenate hands & neck
Promote hair growth
& more

These blood concentrates can be either directly injected just like dermal fillers or topically infused into specific areas of the skin during a microneedling, RF mircroneedling or laser resurfacing treatments.

If you are experiencing hair loss, you’re basically a good candidate for the all-natural PRF hair restoration.

Platelet Rich Fibrin (PRF) is the ultimate blood concentrate.

100% natural, PRF is PRP with superhero powers and amplified results. Clinically there is more volume effect, better skin rejuvenation and longevity. The difference between PRP and PRF lies in how the blood is processed and what kinds of proteins, growth factors, plasma or fibrins, are extracted from the blood. The absence of any additives or anticoagulant in preparation of PRF helps form an all-important fibrin matrix which allows for a slow release of the growth factors over longer period. You’re bathing the area in rich factors for a longer period of time.

The nature of Platelet Therapy procedure may require a patient to return for a series of treatments, spaced 6-8 weeks apart in order to achieve the desired results. Results typically last 1-4 weeks and the volume will essentially dissipate. Long-term effects, such as skin tightening, collagen production and enhanced skin quality, may take up to 3-4 months to be noticed and can last 6 months or longer. Significant results can last as long as two years.

The number of treatments needed is dependent on the area that is being treated as well as the condition that is being addressed. We will discuss this with you at your complimentary consultation. Good general health is the key to excellent and predictable outcomes.

PRF improves under eye pigmentation and skin’s thickness, firmness, and texture while providing very subtle subdermal volume.


PRF Under Eyes ( Tear Troughs )
The under-eye area often called “tear trough”, is the first to age for most people. Multiple techniques are used to address this area and the choice often depends on skin damage, skin texture, bony changes, and fat pad herniation. This a complex area with thin skin and a dynamic component. Outside of surgery, most aesthetic providers use hyaluronic acid fillers to address the area, which are less than ideal with a high rate of patient and provider dissatisfaction. Hyaluronic acid by nature attracts water; a property ill desired in the eye region. PRF contains growth factors and stem cells that are responsible for creating new skin cells, collagen, and blood vessels.

PRF For Hair Restoration
If you are experiencing hair loss, you’re basically a good candidate for PRF hair restoration. PRF hair restoration works best when the patient notices early hair loss as growth factors, white blood cells, stem cells, and platelets in the PRF work best when awakening dormant hair follicles. PRF is also effective for women with traction alopecia, hair thinning caused by hairstyles that pulled the hair to an extreme degree and inhibited hair growth. You will need a series of 3-4 treatments spaced 1 month apart for optimum results (which will be seen 4-9 months following treatments). This treatment requires your blood to be drawn– stay hydrated at least 3-4 days prior to your appointment.

PRF + Microneeding ( Vampire Facial )
Microneedling, or collagen induction therapy, is a popular, procedure known to improve skin texture, the presence of fine lines and scars, and enhance skin appearance. Topical application of growth factors has been shown to improve skin texture and appearance; thus, applying either PRF topically during and immediately after microneedling treatment can improve results by saturating the newly created fine, porous wounds with concentrated growth factors. This is the ultimate anti-aging facial. This treatment requires your blood to be drawn– stay hydrated 3-4 days prior to your appointment.

All-Natural Bio-Filler ( EZGel )
The All Natural Filler or Bio Filler is the latest and the most exciting aesthetic procedure that we have introduced and a 100% natural alternative to synthetic fillers. Natural Filler is produced from components in the patient’s own blood and are injected in a similar fashion as other synthetic fillers to add volume, contour, lift and rejuvenate the skin in areas like face, neck, hands, ect. Natural Filler can be injected in the cheeks, jawline, chin, areas around the eyes & mouth, nasolabial folds, lips, neck, back of the hands, stretch marks and more. The ability to harvest large doses of Natural Filler from a simple blood draw makes Natural Filler an extremely attractive aesthetic procedure with immediate and progressive results.

PRF Anti-Aging Facial Injections
Using your very own blood concentrate, PRF can help restore your youthful, smooth appearance. The injections work overtime, promoting the generation of new collagen which improves the tone and texture of the skin. A series of 3 sessions is recommended 4 weeks apart. Combining PRF Injection with Microneedling or Laser Resurfacing procedures is the ultimate anti-aging facial.

PRF Scar Treatments
Platelet Rich Fibrin is injected or microneedled into the area to diminish the appearance of scarring. Improves scarring from injuries or surgical procedures such as breast augmentation, tummy tuck, knee replacement, etc. You will need a series of 3-4 treatments for optimum results. This treatment requires your blood to be drawn– stay hydrated 3-4 days prior to your appointment.

Combining PRF with Microneedling or Laser Skin Resurfacing is the ultimate anti-aging procedure.

Because PRF treatments essentially use your own blood concentrate, these treatments are extremely safe. As no foreign substances are being injected into your body, there is no risk of an allergic reaction. PRF treatments typically take approximately 60 minutes. 15-30 cc of blood will be drawn from your arm and then spun in a centrifuge. Be sure to drink lots of water before the appointment so we can get a good volume of blood. We prefer not to apply a topical anesthetic. We have some evidence to say that anesthetics can decrease the effectiveness of PRF treatments. However if you prefer to have a topical anesthetic, it can be applied with an understanding that it may affect your results. Once extracted, the concentrate is injected into targeted areas with a fine needle (or cannula) or topically applied during other aesthetic procedures (i.e. Microneedling). The results of your treatment and when you’ll see them are dependent on the area being treated and whether it was injected directly or topically applied. In general you can expect to see results approximately 2-3 weeks following your treatment, and a notable difference around the 4-6 week mark. Your skin will continue to improve over the weeks and months following your treatment. 

The number of treatments is dependent on the area that is being treated as well as the condition that is being addressed. We will discuss this with you at your complimentary consultation.

Do you want to find out if Platelet Therapy is the right aesthetic treatment for you? Contact Avissa Skin clinic today for more information on the best Platelet Therapy Procedures in Ann Arbor Michigan, for information on other cosmetic procedures, or to schedule a consultation. We look forward to hearing from you!